Peutz-Jeghers Syndrome: Symptoms, Causes, Treatments

Learn about Peutz-Jeghers syndrome (PJS) from Cleveland Clinic. See the effects this inherited condition has on the body and how it affects cancer risk.

Peutz-Jeghers Syndrome: What It Is, Symptoms & Genetics Home / Health Library / Diseases & Conditions / Peutz-Jeghers Syndrome Advertisement Advertisement Peutz-Jeghers Syndrome Medically Reviewed. Last updated on 07/26/2023 . Peutz-Jeghers syndrome (PJS) is a genetic disorder. People with PJS develop polyps and dark-colored spots that appear on various parts of their body. They’re also at greater risk for some types of cancer. Advertisement Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic produc

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