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Malignancy-related superior vena cava syndrome - UpToDate

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Malignancy-related superior vena cava syndrome Authors:Reed E Drews, MDDmitry J Rabkin, MD, PhDAlbeir Y Mousa, MD, FACS, MBA, MPH, RPVI Section Editors:Eduardo Bruera, MDNestor L Muller, MD, PhD Deputy Editors:Kathryn A Collins, MD, PhD, FSVS, FACSSadhna R Vora, MD Literature review current through: Aug 2026. This topic last updated: Mar 04, 2025. INTRODUCTION Superior vena cava (SVC) syndrome results from any condition that leads to obstruction of blood flow through the SVC. Malignant obstruction can be caused by direct invasion of the tumor into the SVC or by external compression of…

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