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Lymphatic or Hematogenous Dissemination: How Does a Metastatic Tumor Cell Decide? - PMC

ncbi.nlm.nih.gov · 6,103 words · saved by 1 readers

The .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site. The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Preview improvements coming to the PMC website in October 2024. Learn More or Try it out now. The formation of distant metastases is the deadliest phase of cancer progression. Although numerous studies have identified genes and mechanisms that affect metastasis after tumors have reached secondary sites, our knowledge about how cancer cells initially gain access to systemic circulation is limited. Since tumors can enter the blood directly by intravasating into venous capillaries or indirectly via lymphatics, it is important to evaluate the relative

. Author manuscript; available in PMC: 2006 May 11. Published in final edited form as: Cell Cycle. 2006 Apr 17;5(8):812–817. doi: 10.4161/cc.5.8.2646 Abstract The formation of distant metastases is the deadliest phase of cancer progression. Although numerous studies have identified genes and mechanisms that affect metastasis after tumors have reached secondary sites, our knowledge about how cancer cells initially gain access to systemic circulation is limited. Since tumors can enter the blood directly by intravasating into venous capillaries or indirectly via lymphatics, it is important…

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