Define TGF Beta
Skip to main content Accessibility help AI Mode All Images Videos Forums Short videos News More Tools Function In humans Disease Search Results AI Overview Transforming growth factor beta (TGF-beta) is a multifunctional protein (cytokine) that controls key cellular processes such as growth, division, differentiation, and death (apoptosis). Wikipedia +2 Key Functions Cell Control: Despite its name, it usually acts as a brake on cell growth and helps maintain tissue stability. Immune Regulation: It dampens immune responses and keeps inflammation in check. Tissue Repair: It aids in wound healing by guiding cell movement and scar formation. Nature +5 How It Works (Signaling) It binds to receptor proteins on the surface of cells (type I and type II receptors). This binding triggers a chain reaction inside the cell, largely through messenger molecules called SMADs. The SMAD molecules travel to the cell nucleus to turn specific genes on or off. Sino Biological +5 Role in Disease Cancer: