Nonhomologous end joining and V(D)J recombination require an additional factor - PubMed
pubmed.ncbi.nlm.nih.gov · saved by 1 readers
DNA nonhomologous end-joining (NHEJ) is the major pathway for repairing DNA double-strand breaks in mammalian cells. It also functions to carry out rearrangements at the specialized breaks introduced during V(D)J recombination. Here, we describe a patient with T(-)B(-) severe combined immunodeficien …